Health
Late Diagnoses Lead to Alarming Rise in Gallbladder Cancer Cases in the US
United States: Recent research reveals that black Americans are currently experiencing a higher incidence of gallbladder cancer than before, while this cancer incidence has not significantly changed and, in some cases, even reduced for the rest of the American population.
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Moreover, there is a growing number of cases among Black people where the disease is detected when the patients are in the late stage, as reported by the research presented at Digestive Disease Week (DDW) on Monday in Washington, D.C.
Dr. Yazan Abboud, the lead researcher and an internal medicine resident at Rutgers University New Jersey Medical School, said, “Gallbladder cancer diagnosis at a late stage can be highly detrimental, and increasing a person’s risk of death and leading to more intensive and complex cancer treatment,” as US News reported.

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The researchers pointed out that gallbladder cancer either has very few symptoms or none at all in its initial stages that might be indicative of the ailment.
For this research, the scientists investigated the data of nearly 77,000 patients with gallbladder cancer in the United States, identified in 2001-2020, in the US Cancer Institute’s database, representing nearly 98 percent of the population of the USA.
It was found that the gallbladder cancer incidence remained similar for the white population and reduced at an average rate of 0.6 percent.
However, for gallbladder cancer, age-adjusted mortalities rose greater than 1 percent each year on average for Blacks. There was also a regular yearly increase in the number of cases of newly-detected, late-stage tumors by 3 percent on average.
Abboud said, “This could be due to a lack of timely access to healthcare leading to delayed diagnosis,” as US News reported.
Gallbladder cancer has been identified as one of the most destructive forms of cancer in the world, with the 5-year survival rate standing at only 19 percent, as the experts revealed.
Regarding stages of the disease, nearly 43 percent of cancer cases in the current study were in the advanced stage, and this was more prevalent in Black patients, with about 44 percent of their cancers being at the advanced stage as compared to the White and Hispanic patients whose cancer was at the advanced stage 41 percent.
Researchers said that some of the final signs include having abdominal pain or feeling bloated, losing weight without any change in the diet and having the skin and the whites of the eyes become yellow.
Further research has to be conducted in the future on the causes for these disparities across racial groups, with hopes of narrowing down detection in its early stages, as Abboud noted.
Health
The Silent Killer in Your Shampoo? New Study Links Common Chemicals to Hundreds of Thousands of Deaths

Synthetic elements known as phthalates, infused into countless day-to-day commodities—from food wraps and children’s playthings to beauty essentials—may have silently orchestrated over 10 percent of all global cardiac deaths in adults aged 55 to 64 during 2018, according to a revelatory inquiry.
Dr. Leonardo Trasande, an eminent pediatric and public health specialist at NYU Grossman School of Medicine, emphasized the internal havoc triggered by these substances. “Phthalates ignite widespread arterial inflammation,” he stated, “fast-tracking existing cardiovascular decay and prompting sudden, often fatal, incidents,” according to CNN.
Moreover, Trasande highlighted their interference with testosterone equilibrium, a known forecast marker of heart disease in men. The implications ripple far wider—prior investigations have correlated phthalates with disrupted genital development in infants, diminished sperm production, hormonal instability, asthma, early-onset obesity, and oncological threats.
Dr. David Andrews, interim science lead at the Environmental Working Group, though uninvolved in the research, stressed the urgent importance of its revelations. He declared the data “reinforces the profound physiological and economic price society bears due to DEHP saturation.”
Unsurprisingly, the American Chemistry Council, representing industrial interests, sidestepped substantive comment but reaffirmed its backing of high-molecular phthalates like DINP and DIDP, citing their utility.
Omnipresence of Phthalates: A Stealthy Threat
Nicknamed “everywhere chemicals,” phthalates infiltrate an astounding spectrum of consumer goods—vinyl flooring, garden equipment, medical tubing, furniture, automotive parts, and even waterproof or stain-resistant textiles. Their primary purpose? To enhance material flexibility and endurance, as per CNN.
Personal care products—shampoos, sprays, fragrances, cosmetics—are especially riddled with these agents to preserve scent longevity. Food packaging and synthetic clothing serve as further reservoirs. Inhalation of polluted air or ingestion of contaminated edibles introduces phthalates into the human bloodstream, per the US Centers for Disease Control and Prevention.
Global Lens: DEHP’s Grasp Across Nations
Published in eBiomedicine, the novel research dissected the mortality impact of Di(2-ethylhexyl)phthalate (DEHP) across 200 territories. By scrutinizing health records and environmental data—including urinary traces of DEHP residue—scientists discovered clear correlations to cardiovascular lethality.
DEHP’s reputation precedes it. California’s Proposition 65 flags it for birth anomalies, cancer, and reproductive damage, particularly in males.
The team juxtaposed chemical exposure data against mortality stats from the Institute for Health Metrics and Evaluation, estimating 368,764 global deaths in 2018 tied to DEHP among adults aged 55–64. Notably, Africa bore 30 percent of these fatalities, trailed by East Asia and the Middle East, each accounting for 25 percent.
Study lead Sara Hyman, an NYU research scientist, stated, “This breakthrough estimation spotlights the global danger of phthalates and underscores their insidious impact on human longevity.”
Still, limitations arise. Andrews cautioned against using US-derived hazard ratios to extrapolate for diverse populations, noting variations in exposure, healthcare access, and diagnostic capabilities, as reported by CNN.
Domestic Echoes: Earlier US-Centered Data
In a preceding US study, Trasande’s group tracked phthalate levels in 5,000+ adults over a decade. The findings were grim: Phthalates could be fueling 91,000 to 107,000 premature deaths annually among older Americans.
Even when controlling for diabetes, obesity, existing cardiac issues, diet, physical habits, and other disruptors like bisphenol A (BPA), the association between phthalate exposure and death remained stark. Economic losses tied to these preventable deaths hover between USD 40 billion and USD 47 billion per year in the US alone.
Protective Measures: Shrinking Daily Chemical Load
Experts insist phthalate exposure can be curbed through conscious choices:
– Eschew plasticware, especially for heating or storing food.
– Choose fragrance-free lotions and detergents.
– Opt for unscented or plant-based household cleaners.
– Use glass, metal, wood, or ceramic containers.
– Prefer fresh or frozen produce over canned goods.
– Wash hands regularly to slough off residual contaminants.
– Avoid air fresheners and steer clear of plastics labeled No. 3, 6, or 7.
As Trasande advised, “Minimizing processed food intake and avoiding plastics in heat-heavy environments like microwaves can substantially reduce your body’s chemical burden,” according to CNN.
Conclusion: A Quiet Danger Now Loud and Clear
The modern world is drenched in inconvenience, but often at a cost, we don’t immediately perceive. With growing scientific consensus linking phthalates to global mortality, the evidence demands action, both individually and systemically.
Are we willing to reevaluate our habits for the sake of heartbeats yet to be lost?
Health
Are Your Daily Habits Remodeling Your Brain? Find Out!
United States: As experts note, if one skips a workout or stays up late, his/her brain might still be paying for it even two weeks from now.
The team of researchers from Aalto University and the University of Oulu in Finland have presented how our lifelong daily behaviors influence brain connectivity and how they remain remodeled throughout our lifespan, thus providing valuable grounds for understanding neural plasticity.
More about the finding
Researchers are now very specific that the ways our brains communicate also change, rather than staying the same over a long time, in response to recent experiences over a long extended time period.
Moreover, they also rejected several principles of brain function stability and opened the consciousness of the influence of human daily habits on the neural network, studyfinds.org reported.
The particular experimental design of this study was examined in one subject over the span of five months and reported in PLOS Biology.

Are Your Daily Habits Remodeling Your Brain? Find Out! Credit | Adobe Stock
By acquiring a brain image every few days and integrating it with data donated by wearables and smartphones, the researchers were able to assess how such pre-mentioned variables as sleep quality, physical activity, mood, and even heart rate variability affect the connectivity of the brain.
Further details of the analysis
The participant, Ana Triana, was also the main researcher in the study and received thirty scans over fifteen weeks.
Each scan involved four different tasks: simple attention task, working memory task, resting state, and then execution of watching the movie.
This variation helped the researchers to trace how various types of brain activities changed along with everyday perceptions.
At the same time, monitoring devices of her sleep/wake cycle, physical movements, and data about her heart and breathing rates were collected.
Simple events can leave “echoes” in our brain for up to 15 days! 🧠@AnaM_Triana and her colleagues were tracking one person’s brain and behavioural activity for five months using brain scans and wearable technology.@JariSaramaki @MedicalReel @eglereanhttps://t.co/Mxm7qRsltF
— Aalto University (@AaltoUniversity) October 9, 2024
The mobile application is used to capture the moods and events of each day. This integration of brain scans and actigraphy gave us an extremely high-resolution picture of how daily experience and brain activity were related, studyfinds.org reported.
The study revealed two distinct patterns of brain response: A brief wave, which lasts for a period of up to seven days, and a long-term wave, which can go up to fifteen days.
Results of the study
One of the interesting outcomes was a strong connection between heart rate variability – which is a measure of the heart’s adaptability – and brain connectivity while resting.
It shows that activities that affect our body’s relaxation response, like stress management ways, can shape our brain wiring even when we’re not actively concentrating on a task.
Health
US Obesity Crisis: 40% of Americans Now Obese – What’s Going On?
United States: Obesity remains a huge problem for Americans as far as their health is concerned. New data received by the governments indicate severe obesity, a condition that involves storing far too much fat in the body, has risen to a great extent in the last decade.
More about the study
About 40 percent of the population in the US is obese, according to a 2021-2023 survey of about 6,000 people.
Overall, 9 percent of those polled said they were suffering from severe obesity, according to the US Centers for Disease Control and Prevention (CDC).
Moreover, women were nearly two times as likely as men to report severe obesity.
The general obesity rate looked to have decreased in comparison to what was observed in the 2017-2020 survey. However, it was not considered as a statistically significant change.

US Obesity Crisis: 40% of Americans Now Obese – What’s Going On? Credit | USA TODAY
That is, the numbers are small enough that there exists a probability that the rates did not fall at all.
What more are the experts stating?
Dr. Samuel Emmerich conducted the latest study for CDC as a public health officer. He said it is still early to determine its impact on the disease, including new obesity treatments, which include weight-loss drugs like Wegovy and Zepbound.
What they found is that the combined obesity estimate of the United States in the last decade has not considerably altered.
According to Emmerich, “We simply can’t see down to that detailed level to prescription medication use and compare that to changes in obesity prevalence.”
The prevalence of severe obesity increased from nearly eight percent in the study between 2013 and 2014 to nearly 10 percent in the most recent study.
Prior to that, obesity rates had risen rapidly in the US since the 1990s, according to US federal research.
🇺🇸 — Nearly 40% of Americans are obese, with cases of severe obesity rising sharply, particularly among women, who are nearly twice as likely as men to be severely obese. In 23 states, more than 1 in 3 adults were obese.
🔗 Source
⚡️ @FolkishObserver | 📱 Follow pic.twitter.com/grwzoWKdTR
— Cod (@DocKnows097) October 2, 2024
Obesity and severe obesity are expressed in terms of BMI, which is calculated with the help of height and weight. The above BMI indicates that a person is obese, as per the Food and Drugs Administration.
Super obesity is defined as the condition when the person’s BMI is 40 or more.
Solveig Cunningham is a professor of global health at Emory University who is interested in obesity.
“Seeing increases in severe obesity is even more alarming because that’s the level of obesity that’s most highly associated with some of the highest levels of cardiovascular disease and diabetes and lower quality of life,” Cunningham added.
Cunningham also added that it is not apparent why severe obesity rates were higher among women.
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